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AGAP2-TMEM67 Fusion FISH Probe

The AGAP2-TMEM67 Fusion FISH Probe is used to confirm a fusion of the AGAP2 and TMEM67 genes. The fusion of the AGAP2 and TMEM67 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AGAP2-TMEM67-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AGAP2-TMEM67-20-RERE 20 (40 μL) 200 μL
AGAP2-TMEM67-20-REOR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-REGO 20 (40 μL) 200 μL
AGAP2-TMEM67-20-REGR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-REAQ 20 (40 μL) 200 μL
AGAP2-TMEM67-20-ORRE 20 (40 μL) 200 μL
AGAP2-TMEM67-20-OROR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-ORGO 20 (40 μL) 200 μL
AGAP2-TMEM67-20-ORAQ 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GORE 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GOOR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GOGO 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GOGR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GOAQ 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GRRE 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GROR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GRGO 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GRGR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-GRAQ 20 (40 μL) 200 μL
AGAP2-TMEM67-20-AQRE 20 (40 μL) 200 μL
AGAP2-TMEM67-20-AQOR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-AQGO 20 (40 μL) 200 μL
AGAP2-TMEM67-20-AQGR 20 (40 μL) 200 μL
AGAP2-TMEM67-20-AQAQ 20 (40 μL) 200 μL

TMEM67 Gene Summary

The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6). [provided by RefSeq, Nov 2008]

Gene Name: Transmembrane Protein 67

Chromosome: CHR8: 94767071 -94831460

Locus: 8q22.1

AGAP2 Gene Summary

The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 2

Chromosome: CHR12: 58118075 -58135944

Locus: 12q14.1

Gene Diseases

The AGAP2 TMEM67 Fusion has been associated with the following diseases:

Disease Name
Glioblastoma Multiforme

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.