AGAP2-RAB21 Fusion FISH Probe
The AGAP2-RAB21 Fusion FISH Probe is used to confirm a fusion of the AGAP2 and RAB21 genes. The fusion of the AGAP2 and RAB21 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AGAP2-RAB21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-RERE | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-REOR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-REGO | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-REGR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-REAQ | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-ORRE | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-OROR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-ORGO | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-ORAQ | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GORE | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GOOR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GOGO | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GOGR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GOAQ | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GRRE | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GROR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GRGO | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GRGR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-GRAQ | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-AQRE | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-AQOR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-AQGO | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-AQGR | 20 (40 μL) | 200 μL |
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| AGAP2-RAB21-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB21 Gene Summary
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]
Gene Name: RAB21, Member RAS Oncogene Family
Chromosome: CHR12: 72148657 -72181150
Locus: 12q21.1
AGAP2 Gene Summary
The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 2
Chromosome: CHR12: 58118075 -58135944
Locus: 12q14.1
Gene Diseases
The AGAP2 RAB21 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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