AGAP1-PACRG Fusion FISH Probe
The AGAP1-PACRG Fusion FISH Probe is used to confirm a fusion of the AGAP1 and PACRG genes. The fusion of the AGAP1 and PACRG genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AGAP1-PACRG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-RERE | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-REOR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-REGO | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-REGR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-REAQ | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-ORRE | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-OROR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-ORGO | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-ORAQ | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GORE | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GOOR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GOGO | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GOGR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GOAQ | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GRRE | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GROR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GRGO | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GRGR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-GRAQ | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-AQRE | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-AQOR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-AQGO | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-AQGR | 20 (40 μL) | 200 μL |
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| AGAP1-PACRG-20-AQAQ | 20 (40 μL) | 200 μL |
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AGAP1 Gene Summary
This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 1
Chromosome: CHR2: 236402735 -237034120
Locus: 2q37.2
PACRG Gene Summary
This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Parkin Coregulated
Chromosome: CHR6: 163148163 -163736524
Locus: 6q26
Gene Diseases
The AGAP1 PACRG Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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