AGAP1-ATG4B Fusion FISH Probe
The AGAP1-ATG4B Fusion FISH Probe is used to confirm a fusion of the AGAP1 and ATG4B genes. The fusion of the AGAP1 and ATG4B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AGAP1-ATG4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-RERE | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-REOR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-REGO | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-REGR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-REAQ | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-ORRE | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-OROR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-ORGO | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GORE | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GOOR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GOGO | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GOGR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GRRE | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GROR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GRGO | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GRGR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-AQRE | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-AQOR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-AQGO | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-AQGR | 20 (40 μL) | 200 μL |
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| AGAP1-ATG4B-20-AQAQ | 20 (40 μL) | 200 μL |
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ATG4B Gene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Autophagy Related 4B Cysteine Peptidase
Chromosome: CHR2: 242577026 -242613271
Locus: 2q37.3
AGAP1 Gene Summary
This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 1
Chromosome: CHR2: 236402735 -237034120
Locus: 2q37.2
Gene Diseases
The AGAP1 ATG4B Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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