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AGAP1-ADAMTS2 Fusion FISH Probe

The AGAP1-ADAMTS2 Fusion FISH Probe is used to confirm a fusion of the AGAP1 and ADAMTS2 genes. The fusion of the AGAP1 and ADAMTS2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AGAP1-ADAMTS2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-RERE 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-REOR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-REGO 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-REGR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-REAQ 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-ORRE 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-OROR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-ORGO 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-ORAQ 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GORE 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GOOR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GOGO 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GOGR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GOAQ 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GRRE 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GROR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GRGO 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GRGR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-GRAQ 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-AQRE 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-AQOR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-AQGO 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-AQGR 20 (40 μL) 200 μL
AGAP1-ADAMTS2-20-AQAQ 20 (40 μL) 200 μL

ADAMTS2 Gene Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Gene Name: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 2

Chromosome: CHR5: 178537851 -178772431

Locus: 5q35.3

AGAP1 Gene Summary

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 1

Chromosome: CHR2: 236402735 -237034120

Locus: 2q37.2

Gene Diseases

The AGAP1 ADAMTS2 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.