AFF4-SNTG2 Fusion FISH Probe
The AFF4-SNTG2 Fusion FISH Probe is used to confirm a fusion of the AFF4 and SNTG2 genes. The fusion of the AFF4 and SNTG2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AFF4-SNTG2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-RERE | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-REOR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-REGO | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-REGR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-REAQ | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-ORRE | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-OROR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-ORGO | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-ORAQ | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GORE | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GOOR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GOGO | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GOGR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GOAQ | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GRRE | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GROR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GRGO | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GRGR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-GRAQ | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-AQRE | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-AQOR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-AQGO | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-AQGR | 20 (40 μL) | 200 μL |
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| AFF4-SNTG2-20-AQAQ | 20 (40 μL) | 200 μL |
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AFF4 Gene Summary
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]
Gene Name: AF4/FMR2 Family Member 4
Chromosome: CHR5: 132211070 -132299354
Locus: 5q31.1
SNTG2 Gene Summary
This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008]
Gene Name: Syntrophin Gamma 2
Chromosome: CHR2: 946553 -1371384
Locus: 2p25.3
Gene Diseases
The AFF4 SNTG2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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