AFAP1-NTRK2 Fusion FISH Probe
The AFAP1-NTRK2 Fusion FISH Probe is used to confirm a fusion of the AFAP1 and NTRK2 genes. The fusion of the AFAP1 and NTRK2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AFAP1-NTRK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-RERE | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-REOR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-REGO | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-REGR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-REAQ | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-ORRE | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-OROR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-ORGO | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GORE | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GOOR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GOGO | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GOGR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GRRE | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GROR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GRGO | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GRGR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-AQRE | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-AQOR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-AQGO | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-AQGR | 20 (40 μL) | 200 μL |
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| AFAP1-NTRK2-20-AQAQ | 20 (40 μL) | 200 μL |
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NTRK2 Gene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: Neurotrophic Receptor Tyrosine Kinase 2
Chromosome: CHR9: 87283465 -87638505
Locus: 9q21.33
AFAP1 Gene Summary
The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Actin Filament Associated Protein 1
Chromosome: CHR4: 7760439 -7941653
Locus: 4p16.1
Gene Diseases
The AFAP1 NTRK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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