AFAP1-ABLIM2 Fusion FISH Probe
The AFAP1-ABLIM2 Fusion FISH Probe is used to confirm a fusion of the AFAP1 and ABLIM2 genes. The fusion of the AFAP1 and ABLIM2 genes has been associated with Lung Squamous Cell Carcinoma, Breast Invasive Carcinoma, Breast Invasive Carcinoma, and Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AFAP1-ABLIM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-RERE | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-REOR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-REGO | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-REGR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-REAQ | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-ORRE | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-OROR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-ORGO | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GORE | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GOOR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GOGO | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GOGR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GRRE | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GROR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GRGO | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GRGR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-AQRE | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-AQOR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-AQGO | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-AQGR | 20 (40 μL) | 200 μL |
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| AFAP1-ABLIM2-20-AQAQ | 20 (40 μL) | 200 μL |
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AFAP1 Gene Summary
The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Actin Filament Associated Protein 1
Chromosome: CHR4: 7760439 -7941653
Locus: 4p16.1
ABLIM2 Gene Summary
The Actin Binding LIM Protein Family Member 2 (ABLIM2) gene is located on chr4 :7967036-8160559 at 4p16.1.
Gene Name: Actin Binding LIM Protein Family Member 2
Chromosome: CHR4: 7967036 -8160559
Locus: 4p16.1
Gene Diseases
The AFAP1 ABLIM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Breast Invasive Carcinoma |
| Breast Invasive Carcinoma |
| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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