ADRM1-CCT5 Fusion FISH Probe
The ADRM1-CCT5 Fusion FISH Probe is used to confirm a fusion of the ADRM1 and CCT5 genes. The fusion of the ADRM1 and CCT5 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADRM1-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| ADRM1-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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ADRM1 Gene Summary
This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Adhesion Regulating Molecule 1
Chromosome: CHR20: 60878026 -60883918
Locus: 20q13.33
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The ADRM1 CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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