ADORA2B-SYN3 Fusion FISH Probe
The ADORA2B-SYN3 Fusion FISH Probe is used to confirm a fusion of the ADORA2B and SYN3 genes. The fusion of the ADORA2B and SYN3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADORA2B-SYN3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-RERE | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-REOR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-REGO | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-REGR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-REAQ | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-ORRE | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-OROR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-ORGO | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GORE | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GOOR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GOGO | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GOGR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GRRE | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GROR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GRGO | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GRGR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-AQRE | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-AQOR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-AQGO | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-AQGR | 20 (40 μL) | 200 μL |
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| ADORA2B-SYN3-20-AQAQ | 20 (40 μL) | 200 μL |
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ADORA2B Gene Summary
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Gene Name: Adenosine A2b Receptor
Chromosome: CHR17: 15848230 -15879210
Locus: 17p12
SYN3 Gene Summary
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq, Oct 2008]
Gene Name: Synapsin III
Chromosome: CHR22: 32908539 -33454377
Locus: 22q12.3
Gene Diseases
The ADORA2B SYN3 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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