ADIPOR1-RGS8 Fusion FISH Probe
The ADIPOR1-RGS8 Fusion FISH Probe is used to confirm a fusion of the ADIPOR1 and RGS8 genes. The fusion of the ADIPOR1 and RGS8 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADIPOR1-RGS8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-RERE | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-REOR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-REGO | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-REGR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-REAQ | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-ORRE | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-OROR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-ORGO | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GORE | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GOOR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GOGO | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GOGR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GRRE | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GROR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GRGO | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GRGR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-AQRE | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-AQOR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-AQGO | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-AQGR | 20 (40 μL) | 200 μL |
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| ADIPOR1-RGS8-20-AQAQ | 20 (40 μL) | 200 μL |
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ADIPOR1 Gene Summary
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]
Gene Name: Adiponectin Receptor 1
Chromosome: CHR1: 202909960 -202927700
Locus: 1q32.1
RGS8 Gene Summary
This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008]
Gene Name: Regulator Of G Protein Signaling 8
Chromosome: CHR1: 182615791 -182642067
Locus: 1q25.3
Gene Diseases
The ADIPOR1 RGS8 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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