ADH7-CXCR5 Fusion FISH Probe
The ADH7-CXCR5 Fusion FISH Probe is used to confirm a fusion of the ADH7 and CXCR5 genes. The fusion of the ADH7 and CXCR5 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADH7-CXCR5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-RERE | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-REOR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-REGO | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-REGR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-REAQ | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-ORRE | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-OROR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-ORGO | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GORE | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GOOR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GOGO | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GOGR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GRRE | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GROR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GRGO | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GRGR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-AQRE | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-AQOR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-AQGO | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-AQGR | 20 (40 μL) | 200 μL |
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| ADH7-CXCR5-20-AQAQ | 20 (40 μL) | 200 μL |
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ADH7 Gene Summary
This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Alcohol Dehydrogenase 7 (class IV), Mu Or Sigma Polypeptide
Chromosome: CHR4: 100333417 -100356667
Locus: 4q23
CXCR5 Gene Summary
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: C-X-C Motif Chemokine Receptor 5
Chromosome: CHR11: 118754474 -118766980
Locus: 11q23.3
Gene Diseases
The ADH7 CXCR5 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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