ADD1-ADK Fusion FISH Probe
The ADD1-ADK Fusion FISH Probe is used to confirm a fusion of the ADD1 and ADK genes. The fusion of the ADD1 and ADK genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADD1-ADK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-RERE | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-REOR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-REGO | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-REGR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-REAQ | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-ORRE | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-OROR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-ORGO | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GORE | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GOOR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GOGO | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GOGR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GRRE | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GROR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GRGO | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GRGR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-AQRE | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-AQOR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-AQGO | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-AQGR | 20 (40 μL) | 200 μL |
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| ADD1-ADK-20-AQAQ | 20 (40 μL) | 200 μL |
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ADD1 Gene Summary
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]
Gene Name: Adducin 1
Chromosome: CHR4: 2845583 -2931802
Locus: 4p16.3
ADK Gene Summary
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Adenosine Kinase
Chromosome: CHR10: 75910942 -76469061
Locus: 10q11-q24
Gene Diseases
The ADD1 ADK Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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