ADCY9-NMRAL1 Fusion FISH Probe
The ADCY9-NMRAL1 Fusion FISH Probe is used to confirm a fusion of the ADCY9 and NMRAL1 genes. The fusion of the ADCY9 and NMRAL1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADCY9-NMRAL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-RERE | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-REOR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-REGO | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-REGR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-REAQ | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-ORRE | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-OROR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-ORGO | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GORE | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GOOR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GOGO | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GOGR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GRRE | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GROR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GRGO | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GRGR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-AQRE | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-AQOR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-AQGO | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-AQGR | 20 (40 μL) | 200 μL |
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| ADCY9-NMRAL1-20-AQAQ | 20 (40 μL) | 200 μL |
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ADCY9 Gene Summary
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]
Gene Name: Adenylate Cyclase 9
Chromosome: CHR16: 4012649 -4166186
Locus: 16p13.3
NMRAL1 Gene Summary
This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Name: NmrA Like Redox Sensor 1
Chromosome: CHR16: 4511694 -4524896
Locus: 16p13.3
Gene Diseases
The ADCY9 NMRAL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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