ADCY5-PTPLB Fusion FISH Probe
The ADCY5-PTPLB Fusion FISH Probe is used to confirm a fusion of the ADCY5 and PTPLB genes. The fusion of the ADCY5 and PTPLB genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADCY5-PTPLB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-RERE | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-REOR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-REGO | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-REGR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-REAQ | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-ORRE | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-OROR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-ORGO | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GORE | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GOOR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GOGO | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GOGR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GRRE | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GROR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GRGO | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GRGR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-AQRE | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-AQOR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-AQGO | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-AQGR | 20 (40 μL) | 200 μL |
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| ADCY5-PTPLB-20-AQAQ | 20 (40 μL) | 200 μL |
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ADCY5 Gene Summary
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Adenylate Cyclase 5
Chromosome: CHR3: 123001142 -123167392
Locus: 3q21.1
Gene Diseases
The ADCY5 PTPLB Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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