ADAMTS13-LHX2 Fusion FISH Probe
The ADAMTS13-LHX2 Fusion FISH Probe is used to confirm a fusion of the ADAMTS13 and LHX2 genes. The fusion of the ADAMTS13 and LHX2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADAMTS13-LHX2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-RERE | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-REOR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-REGO | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-REGR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-REAQ | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-ORRE | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-OROR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-ORGO | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GORE | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GOOR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GOGO | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GOGR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GRRE | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GROR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GRGO | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GRGR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-AQRE | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-AQOR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-AQGO | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-AQGR | 20 (40 μL) | 200 μL |
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| ADAMTS13-LHX2-20-AQAQ | 20 (40 μL) | 200 μL |
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LHX2 Gene Summary
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq, Jul 2008]
Gene Name: LIM Homeobox 2
Chromosome: CHR9: 126773888 -126795442
Locus: 9q33.3
ADAMTS13 Gene Summary
This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13
Chromosome: CHR9: 136279458 -136324508
Locus: 9q34.2
Gene Diseases
The ADAMTS13 LHX2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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