ADAM9-RGS20 Fusion FISH Probe
The ADAM9-RGS20 Fusion FISH Probe is used to confirm a fusion of the ADAM9 and RGS20 genes. The fusion of the ADAM9 and RGS20 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADAM9-RGS20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-RERE | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-REOR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-REGO | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-REGR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-REAQ | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-ORRE | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-OROR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-ORGO | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GORE | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GOOR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GOGO | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GOGR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GRRE | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GROR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GRGO | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GRGR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-AQRE | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-AQOR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-AQGO | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-AQGR | 20 (40 μL) | 200 μL |
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| ADAM9-RGS20-20-AQAQ | 20 (40 μL) | 200 μL |
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RGS20 Gene Summary
The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Regulator Of G Protein Signaling 20
Chromosome: CHR8: 54764367 -54871863
Locus: 8q11.23
ADAM9 Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]
Gene Name: ADAM Metallopeptidase Domain 9
Chromosome: CHR8: 38854504 -38962779
Locus: 8p11.22
Gene Diseases
The ADAM9 RGS20 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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