ADAM10-ZNF770 Fusion FISH Probe
The ADAM10-ZNF770 Fusion FISH Probe is used to confirm a fusion of the ADAM10 and ZNF770 genes. The fusion of the ADAM10 and ZNF770 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADAM10-ZNF770-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-RERE | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-REOR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-REGO | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-REGR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-REAQ | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-ORRE | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-OROR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-ORGO | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GORE | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GOOR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GOGO | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GOGR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GRRE | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GROR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GRGO | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GRGR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-AQRE | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-AQOR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-AQGO | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-AQGR | 20 (40 μL) | 200 μL |
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| ADAM10-ZNF770-20-AQAQ | 20 (40 μL) | 200 μL |
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ADAM10 Gene Summary
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016]
Gene Name: ADAM Metallopeptidase Domain 10
Chromosome: CHR15: 58888509 -59042177
Locus: 15q21.3
ZNF770 Gene Summary
The Zinc Finger Protein 770 (ZNF770) gene is located on chr15 :35270541-35280497 at 15q14.
Gene Name: Zinc Finger Protein 770
Chromosome: CHR15: 35270541 -35280497
Locus: 15q14
Gene Diseases
The ADAM10 ZNF770 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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