ACVR1B-SUPT16H Fusion FISH Probe
The ACVR1B-SUPT16H Fusion FISH Probe is used to confirm a fusion of the ACVR1B and SUPT16H genes. The fusion of the ACVR1B and SUPT16H genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACVR1B-SUPT16H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-RERE | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-REOR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-REGO | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-REGR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-REAQ | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-ORRE | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-OROR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-ORGO | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GORE | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GOOR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GOGO | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GOGR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GRRE | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GROR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GRGO | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GRGR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-AQRE | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-AQOR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-AQGO | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-AQGR | 20 (40 μL) | 200 μL |
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| ACVR1B-SUPT16H-20-AQAQ | 20 (40 μL) | 200 μL |
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ACVR1B Gene Summary
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
Gene Name: Activin A Receptor Type 1B
Chromosome: CHR12: 52345450 -52390863
Locus: 12q13.13
SUPT16H Gene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Gene Name: SPT16 Homolog, Facilitates Chromatin Remodeling Subunit
Chromosome: CHR14: 21819630 -21852425
Locus: 14q11.2
Gene Diseases
The ACVR1B SUPT16H Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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