ACTG1-PLEKHA5 Fusion FISH Probe
The ACTG1-PLEKHA5 Fusion FISH Probe is used to confirm a fusion of the ACTG1 and PLEKHA5 genes. The fusion of the ACTG1 and PLEKHA5 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACTG1-PLEKHA5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-RERE | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-REOR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-REGO | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-REGR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-OROR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GORE | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GROR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTG1-PLEKHA5-20-AQAQ | 20 (40 μL) | 200 μL |
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ACTG1 Gene Summary
Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
Gene Name: Actin Gamma 1
Chromosome: CHR17: 79476996 -79479892
Locus: 17q25.3
PLEKHA5 Gene Summary
The Pleckstrin Homology Domain Containing A5 (PLEKHA5) gene is located on chr12 :19282625-19529333 at 12p12.3.
Gene Name: Pleckstrin Homology Domain Containing A5
Chromosome: CHR12: 19282625 -19529333
Locus: 12p12.3
Gene Diseases
The ACTG1 PLEKHA5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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