ACTB-TM4SF4 Fusion FISH Probe
The ACTB-TM4SF4 Fusion FISH Probe is used to confirm a fusion of the ACTB and TM4SF4 genes. The fusion of the ACTB and TM4SF4 genes has been associated with Pancreatic Adenocarcinoma, and Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACTB-TM4SF4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-RERE | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-REOR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-REGO | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-REGR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-OROR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GORE | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GROR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTB-TM4SF4-20-AQAQ | 20 (40 μL) | 200 μL |
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ACTB Gene Summary
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]
Gene Name: Actin Beta
Chromosome: CHR7: 5566778 -5570232
Locus: 7p22.1
TM4SF4 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation.[provided by RefSeq, Mar 2011]
Gene Name: Transmembrane 4 L Six Family Member 4
Chromosome: CHR3: 149192367 -149221181
Locus: 3q25.1
Gene Diseases
The ACTB TM4SF4 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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