ACTB-PMP2 Fusion FISH Probe
The ACTB-PMP2 Fusion FISH Probe is used to confirm a fusion of the ACTB and PMP2 genes. The fusion of the ACTB and PMP2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACTB-PMP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-RERE | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-REOR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-REGO | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-REGR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-OROR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GORE | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GROR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTB-PMP2-20-AQAQ | 20 (40 μL) | 200 μL |
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ACTB Gene Summary
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]
Gene Name: Actin Beta
Chromosome: CHR7: 5566778 -5570232
Locus: 7p22.1
PMP2 Gene Summary
The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy. [provided by RefSeq, Jan 2017]
Gene Name: Peripheral Myelin Protein 2
Chromosome: CHR8: 82352563 -82359719
Locus: 8q21.13
Gene Diseases
The ACTB PMP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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