ACTB-COL17A1 Fusion FISH Probe
The ACTB-COL17A1 Fusion FISH Probe is used to confirm a fusion of the ACTB and COL17A1 genes. The fusion of the ACTB and COL17A1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACTB-COL17A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-RERE | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-REOR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-REGO | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-REGR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-OROR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GORE | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GROR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTB-COL17A1-20-AQAQ | 20 (40 μL) | 200 μL |
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ACTB Gene Summary
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]
Gene Name: Actin Beta
Chromosome: CHR7: 5566778 -5570232
Locus: 7p22.1
COL17A1 Gene Summary
This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
Gene Name: Collagen Type XVII Alpha 1 Chain
Chromosome: CHR10: 105791045 -105845638
Locus: 10q25.1
Gene Diseases
The ACTB COL17A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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