ACTB-CDC5L Fusion FISH Probe
The ACTB-CDC5L Fusion FISH Probe is used to confirm a fusion of the ACTB and CDC5L genes. The fusion of the ACTB and CDC5L genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACTB-CDC5L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-RERE | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-REOR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-REGO | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-REGR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-OROR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GORE | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GROR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTB-CDC5L-20-AQAQ | 20 (40 μL) | 200 μL |
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ACTB Gene Summary
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]
Gene Name: Actin Beta
Chromosome: CHR7: 5566778 -5570232
Locus: 7p22.1
CDC5L Gene Summary
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. [provided by RefSeq, Jul 2008]
Gene Name: Cell Division Cycle 5 Like
Chromosome: CHR6: 44355301 -44414780
Locus: 6p21.1
Gene Diseases
The ACTB CDC5L Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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