ACSL6-CDS2 Fusion FISH Probe
The ACSL6-CDS2 Fusion FISH Probe is used to confirm a fusion of the ACSL6 and CDS2 genes. The fusion of the ACSL6 and CDS2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACSL6-CDS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-RERE | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-REOR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-REGO | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-REGR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-REAQ | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-ORRE | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-OROR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-ORGO | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GORE | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GOOR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GOGO | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GOGR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GRRE | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GROR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GRGO | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GRGR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-AQRE | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-AQOR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-AQGO | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-AQGR | 20 (40 μL) | 200 μL |
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| ACSL6-CDS2-20-AQAQ | 20 (40 μL) | 200 μL |
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CDS2 Gene Summary
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]
Gene Name: CDP-diacylglycerol Synthase 2
Chromosome: CHR20: 5107406 -5178533
Locus: 20p12.3
ACSL6 Gene Summary
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
Gene Name: Acyl-CoA Synthetase Long Chain Family Member 6
Chromosome: CHR5: 131285666 -131347761
Locus: 5q31.1
Gene Diseases
The ACSL6 CDS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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