ACSL3-SGPP2 Fusion FISH Probe
The ACSL3-SGPP2 Fusion FISH Probe is used to confirm a fusion of the ACSL3 and SGPP2 genes. The fusion of the ACSL3 and SGPP2 genes has been associated with Prostate Adenocarcinoma, and Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACSL3-SGPP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-RERE | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-REOR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-REGO | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-REGR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-REAQ | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-ORRE | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-OROR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-ORGO | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GORE | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GOOR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GOGO | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GOGR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GRRE | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GROR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GRGO | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GRGR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-AQRE | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-AQOR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-AQGO | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-AQGR | 20 (40 μL) | 200 μL |
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| ACSL3-SGPP2-20-AQAQ | 20 (40 μL) | 200 μL |
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ACSL3 Gene Summary
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Acyl-CoA Synthetase Long Chain Family Member 3
Chromosome: CHR2: 223725731 -223808119
Locus: 2q36.1
SGPP2 Gene Summary
The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Sphingosine-1-phosphate Phosphatase 2
Chromosome: CHR2: 223289321 -223423617
Locus: 2q36.1
Gene Diseases
The ACSL3 SGPP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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