ACSF3-MYH7B Fusion FISH Probe
The ACSF3-MYH7B Fusion FISH Probe is used to confirm a fusion of the ACSF3 and MYH7B genes. The fusion of the ACSF3 and MYH7B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACSF3-MYH7B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-RERE | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-REOR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-REGO | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-REGR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-REAQ | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-ORRE | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-OROR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-ORGO | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GORE | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GOOR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GOGO | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GOGR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GRRE | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GROR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GRGO | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GRGR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-AQRE | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-AQOR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-AQGO | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-AQGR | 20 (40 μL) | 200 μL |
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| ACSF3-MYH7B-20-AQAQ | 20 (40 μL) | 200 μL |
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MYH7B Gene Summary
The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]
Gene Name: Myosin Heavy Chain 7B
Chromosome: CHR20: 33543703 -33590240
Locus: 20q11.22
ACSF3 Gene Summary
This gene encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Acyl-CoA Synthetase Family Member 3
Chromosome: CHR16: 89160216 -89222171
Locus: 16q24.3
Gene Diseases
The ACSF3 MYH7B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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