ACOX3-STAT1 Fusion FISH Probe
The ACOX3-STAT1 Fusion FISH Probe is used to confirm a fusion of the ACOX3 and STAT1 genes. The fusion of the ACOX3 and STAT1 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACOX3-STAT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ACOX3-STAT1-20-AQAQ | 20 (40 μL) | 200 μL |
|
STAT1 Gene Summary
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Signal Transducer And Activator Of Transcription 1
Chromosome: CHR2: 191833761 -191878976
Locus: 2q32.2
ACOX3 Gene Summary
Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008]
Gene Name: Acyl-CoA Oxidase 3, Pristanoyl
Chromosome: CHR4: 8368008 -8442452
Locus: 4p16.1
Gene Diseases
The ACOX3 STAT1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|