ACOT7-NSMCE2 Fusion FISH Probe
The ACOT7-NSMCE2 Fusion FISH Probe is used to confirm a fusion of the ACOT7 and NSMCE2 genes. The fusion of the ACOT7 and NSMCE2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACOT7-NSMCE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-RERE | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-REOR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-REGO | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-REGR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-REAQ | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-ORRE | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-OROR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-ORGO | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GORE | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GOOR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GOGO | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GOGR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GRRE | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GROR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GRGO | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GRGR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-AQRE | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-AQOR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-AQGO | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-AQGR | 20 (40 μL) | 200 μL |
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| ACOT7-NSMCE2-20-AQAQ | 20 (40 μL) | 200 μL |
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ACOT7 Gene Summary
This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Acyl-CoA Thioesterase 7
Chromosome: CHR1: 6324331 -6453826
Locus: 1p36.31
NSMCE2 Gene Summary
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]
Gene Name: NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase
Chromosome: CHR8: 126104082 -126379367
Locus: 8q24.13
Gene Diseases
The ACOT7 NSMCE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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