ACO2-AHRR Fusion FISH Probe
The ACO2-AHRR Fusion FISH Probe is used to confirm a fusion of the ACO2 and AHRR genes. The fusion of the ACO2 and AHRR genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACO2-AHRR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-RERE | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-REOR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-REGO | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-REGR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-REAQ | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-ORRE | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-OROR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-ORGO | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GORE | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GOOR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GOGO | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GOGR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GRRE | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GROR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GRGO | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GRGR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-AQRE | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-AQOR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-AQGO | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-AQGR | 20 (40 μL) | 200 μL |
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| ACO2-AHRR-20-AQAQ | 20 (40 μL) | 200 μL |
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ACO2 Gene Summary
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]
Gene Name: Aconitase 2
Chromosome: CHR22: 41865128 -41924993
Locus: 22q13.2
AHRR Gene Summary
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
Gene Name: Aryl-hydrocarbon Receptor Repressor
Chromosome: CHR5: 304290 -438405
Locus: 5p15.33
Gene Diseases
The ACO2 AHRR Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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