ACLY-WEE1 Fusion FISH Probe
The ACLY-WEE1 Fusion FISH Probe is used to confirm a fusion of the ACLY and WEE1 genes. The fusion of the ACLY and WEE1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACLY-WEE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-RERE | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-REOR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-REGO | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-REGR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-REAQ | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-ORRE | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-OROR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-ORGO | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GORE | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GOOR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GOGO | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GOGR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GRRE | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GROR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GRGO | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GRGR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-AQRE | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-AQOR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-AQGO | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-AQGR | 20 (40 μL) | 200 μL |
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| ACLY-WEE1-20-AQAQ | 20 (40 μL) | 200 μL |
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ACLY Gene Summary
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
Gene Name: ATP Citrate Lyase
Chromosome: CHR17: 40023178 -40075272
Locus: 17q21.2
WEE1 Gene Summary
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008]
Gene Name: WEE1 G2 Checkpoint Kinase
Chromosome: CHR11: 9595227 -9611313
Locus: 11p15.4
Gene Diseases
The ACLY WEE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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