ACER2-C8ORF37 Fusion FISH Probe
The ACER2-C8ORF37 Fusion FISH Probe is used to confirm a fusion of the ACER2 and C8ORF37 genes. The fusion of the ACER2 and C8ORF37 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACER2-C8ORF37-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-RERE | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-REOR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-REGO | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-REGR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-REAQ | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-ORRE | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-OROR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-ORGO | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GORE | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GOOR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GOGO | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GOGR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GRRE | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GROR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GRGO | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GRGR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-AQRE | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-AQOR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-AQGO | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-AQGR | 20 (40 μL) | 200 μL |
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| ACER2-C8ORF37-20-AQAQ | 20 (40 μL) | 200 μL |
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C8orf37 Gene Summary
This gene encodes a ubiquitously expressed protein of unknown function. It has high levels of mRNA expression in the brain, heart, and retina and the protein co-localizes with polyglutamylated tubulin at the base of the primary cilium in human retinal pigment epithelial cells. Mutations in this gene have been associated with autosomal recessive cone-rod dystrophy (arCRD) and retinitis pigmentosa (arRP). [provided by RefSeq, Mar 2012]
Gene Name: Chromosome 8 Open Reading Frame 37
Chromosome: CHR8: 96257140 -96281462
Locus: 8q22.1
ACER2 Gene Summary
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010]
Gene Name: Alkaline Ceramidase 2
Chromosome: CHR9: 19408924 -19452500
Locus: 9p22.1
Gene Diseases
The ACER2 C8ORF37 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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