ACE2-GPR143 Fusion FISH Probe
The ACE2-GPR143 Fusion FISH Probe is used to confirm a fusion of the ACE2 and GPR143 genes. The fusion of the ACE2 and GPR143 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACE2-GPR143-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-RERE | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-REOR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-REGO | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-REGR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-REAQ | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-ORRE | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-OROR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-ORGO | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GORE | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GOOR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GOGO | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GOGR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GRRE | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GROR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GRGO | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GRGR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-AQRE | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-AQOR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-AQGO | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-AQGR | 20 (40 μL) | 200 μL |
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| ACE2-GPR143-20-AQAQ | 20 (40 μL) | 200 μL |
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GPR143 Gene Summary
This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]
Gene Name: G Protein-coupled Receptor 143
Chromosome: CHRX: 9693452 -9734005
Locus: Xp22.2
ACE2 Gene Summary
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
Gene Name: Angiotensin I Converting Enzyme 2
Chromosome: CHRX: 15579155 -15620192
Locus: Xp22.2
Gene Diseases
The ACE2 GPR143 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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