ACAP3-DVL1 Fusion FISH Probe
The ACAP3-DVL1 Fusion FISH Probe is used to confirm a fusion of the ACAP3 and DVL1 genes. The fusion of the ACAP3 and DVL1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACAP3-DVL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-RERE | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-REOR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-REGO | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-REGR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-REAQ | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-ORRE | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-OROR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-ORGO | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GORE | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GOOR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GOGO | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GOGR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GRRE | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GROR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GRGO | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GRGR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-AQRE | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-AQOR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-AQGO | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-AQGR | 20 (40 μL) | 200 μL |
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| ACAP3-DVL1-20-AQAQ | 20 (40 μL) | 200 μL |
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DVL1 Gene Summary
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008]
Gene Name: Dishevelled Segment Polarity Protein 1
Chromosome: CHR1: 1270657 -1284492
Locus: 1p36.33
ACAP3 Gene Summary
The ArfGAP With Coiled-coil, Ankyrin Repeat And PH Domains 3 (ACAP3) gene is located on chr1 :1227763-1243269 at 1p36.33.
Gene Name: ArfGAP With Coiled-coil, Ankyrin Repeat And PH Domains 3
Chromosome: CHR1: 1227763 -1243269
Locus: 1p36.33
Gene Diseases
The ACAP3 DVL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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