ACACA-ADAM9 Fusion FISH Probe
The ACACA-ADAM9 Fusion FISH Probe is used to confirm a fusion of the ACACA and ADAM9 genes. The fusion of the ACACA and ADAM9 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACACA-ADAM9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-RERE | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-REOR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-REGO | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-REGR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-REAQ | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-ORRE | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-OROR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-ORGO | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GORE | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GOOR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GOGO | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GOGR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GRRE | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GROR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GRGO | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GRGR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-AQRE | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-AQOR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-AQGO | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-AQGR | 20 (40 μL) | 200 μL |
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| ACACA-ADAM9-20-AQAQ | 20 (40 μL) | 200 μL |
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ACACA Gene Summary
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Acetyl-CoA Carboxylase Alpha
Chromosome: CHR17: 35441926 -35766902
Locus: 17q12
ADAM9 Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]
Gene Name: ADAM Metallopeptidase Domain 9
Chromosome: CHR8: 38854504 -38962779
Locus: 8p11.22
Gene Diseases
The ACACA ADAM9 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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