ABLIM1-PDE6B Fusion FISH Probe
The ABLIM1-PDE6B Fusion FISH Probe is used to confirm a fusion of the ABLIM1 and PDE6B genes. The fusion of the ABLIM1 and PDE6B genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABLIM1-PDE6B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-RERE | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-REOR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-REGO | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-REGR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-REAQ | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-ORRE | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-OROR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-ORGO | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GORE | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GOOR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GOGO | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GOGR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GRRE | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GROR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GRGO | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GRGR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-AQRE | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-AQOR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-AQGO | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-AQGR | 20 (40 μL) | 200 μL |
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| ABLIM1-PDE6B-20-AQAQ | 20 (40 μL) | 200 μL |
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ABLIM1 Gene Summary
This gene encodes a LIM zinc-binding domain-containing protein that binds to actin filaments and mediates interactions between actin and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2017]
Gene Name: Actin Binding LIM Protein 1
Chromosome: CHR10: 116190868 -116444414
Locus: 10q25.3
PDE6B Gene Summary
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Gene Name: Phosphodiesterase 6B
Chromosome: CHR4: 619362 -664681
Locus: 4p16.3
Gene Diseases
The ABLIM1 PDE6B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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