ABHD2-ACAN Fusion FISH Probe
The ABHD2-ACAN Fusion FISH Probe is used to confirm a fusion of the ABHD2 and ACAN genes. The fusion of the ABHD2 and ACAN genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABHD2-ACAN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-RERE | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-REOR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-REGO | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-REGR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-REAQ | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-ORRE | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-OROR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-ORGO | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GORE | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GOOR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GOGO | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GOGR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GRRE | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GROR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GRGO | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GRGR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-AQRE | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-AQOR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-AQGO | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-AQGR | 20 (40 μL) | 200 μL |
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| ABHD2-ACAN-20-AQAQ | 20 (40 μL) | 200 μL |
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ACAN Gene Summary
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]
Gene Name: Aggrecan
Chromosome: CHR15: 89346673 -89418585
Locus: 15q26.1
ABHD2 Gene Summary
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a wide range of enzymes. The encoded protein is an acylglycerol lipase that catalyzes the hydrolysis of endocannabinoid arachidonoylglycerol from the cell membrane. This leads to activation of the sperm calcium channel CatSper, which results in sperm activation. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jan 2017]
Gene Name: Abhydrolase Domain Containing 2
Chromosome: CHR15: 89631380 -89745591
Locus: 15q26.1
Gene Diseases
The ABHD2 ACAN Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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