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ABHD12-GINS1 Fusion FISH Probe

The ABHD12-GINS1 Fusion FISH Probe is used to confirm a fusion of the ABHD12 and GINS1 genes. The fusion of the ABHD12 and GINS1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABHD12-GINS1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABHD12-GINS1-20-RERE 20 (40 μL) 200 μL
ABHD12-GINS1-20-REOR 20 (40 μL) 200 μL
ABHD12-GINS1-20-REGO 20 (40 μL) 200 μL
ABHD12-GINS1-20-REGR 20 (40 μL) 200 μL
ABHD12-GINS1-20-REAQ 20 (40 μL) 200 μL
ABHD12-GINS1-20-ORRE 20 (40 μL) 200 μL
ABHD12-GINS1-20-OROR 20 (40 μL) 200 μL
ABHD12-GINS1-20-ORGO 20 (40 μL) 200 μL
ABHD12-GINS1-20-ORAQ 20 (40 μL) 200 μL
ABHD12-GINS1-20-GORE 20 (40 μL) 200 μL
ABHD12-GINS1-20-GOOR 20 (40 μL) 200 μL
ABHD12-GINS1-20-GOGO 20 (40 μL) 200 μL
ABHD12-GINS1-20-GOGR 20 (40 μL) 200 μL
ABHD12-GINS1-20-GOAQ 20 (40 μL) 200 μL
ABHD12-GINS1-20-GRRE 20 (40 μL) 200 μL
ABHD12-GINS1-20-GROR 20 (40 μL) 200 μL
ABHD12-GINS1-20-GRGO 20 (40 μL) 200 μL
ABHD12-GINS1-20-GRGR 20 (40 μL) 200 μL
ABHD12-GINS1-20-GRAQ 20 (40 μL) 200 μL
ABHD12-GINS1-20-AQRE 20 (40 μL) 200 μL
ABHD12-GINS1-20-AQOR 20 (40 μL) 200 μL
ABHD12-GINS1-20-AQGO 20 (40 μL) 200 μL
ABHD12-GINS1-20-AQGR 20 (40 μL) 200 μL
ABHD12-GINS1-20-AQAQ 20 (40 μL) 200 μL

GINS1 Gene Summary

The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).[supplied by OMIM, Mar 2008]

Gene Name: GINS Complex Subunit 1

Chromosome: CHR20: 25388322 -25429191

Locus: 20p11.21

ABHD12 Gene Summary

This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]

Gene Name: Abhydrolase Domain Containing 12

Chromosome: CHR20: 25275378 -25371618

Locus: 20p11.21

Gene Diseases

The ABHD12 GINS1 Fusion has been associated with the following diseases:

Disease Name
Colon Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.