ABHD12-ENTPD6 Fusion FISH Probe
The ABHD12-ENTPD6 Fusion FISH Probe is used to confirm a fusion of the ABHD12 and ENTPD6 genes. The fusion of the ABHD12 and ENTPD6 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABHD12-ENTPD6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-RERE | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-REOR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-REGO | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-REGR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-REAQ | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-ORRE | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-OROR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-ORGO | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GORE | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GOOR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GOGO | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GOGR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GRRE | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GROR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GRGO | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GRGR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-AQRE | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-AQOR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-AQGO | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-AQGR | 20 (40 μL) | 200 μL |
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| ABHD12-ENTPD6-20-AQAQ | 20 (40 μL) | 200 μL |
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ENTPD6 Gene Summary
ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which are characteristic of NTPases. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Name: Ectonucleoside Triphosphate Diphosphohydrolase 6 (putative)
Chromosome: CHR20: 25176338 -25207360
Locus: 20p11.21
ABHD12 Gene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
Gene Name: Abhydrolase Domain Containing 12
Chromosome: CHR20: 25275378 -25371618
Locus: 20p11.21
Gene Diseases
The ABHD12 ENTPD6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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