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ABCG1-BACE2 Fusion FISH Probe

The ABCG1-BACE2 Fusion FISH Probe is used to confirm a fusion of the ABCG1 and BACE2 genes. The fusion of the ABCG1 and BACE2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABCG1-BACE2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABCG1-BACE2-20-RERE 20 (40 μL) 200 μL
ABCG1-BACE2-20-REOR 20 (40 μL) 200 μL
ABCG1-BACE2-20-REGO 20 (40 μL) 200 μL
ABCG1-BACE2-20-REGR 20 (40 μL) 200 μL
ABCG1-BACE2-20-REAQ 20 (40 μL) 200 μL
ABCG1-BACE2-20-ORRE 20 (40 μL) 200 μL
ABCG1-BACE2-20-OROR 20 (40 μL) 200 μL
ABCG1-BACE2-20-ORGO 20 (40 μL) 200 μL
ABCG1-BACE2-20-ORAQ 20 (40 μL) 200 μL
ABCG1-BACE2-20-GORE 20 (40 μL) 200 μL
ABCG1-BACE2-20-GOOR 20 (40 μL) 200 μL
ABCG1-BACE2-20-GOGO 20 (40 μL) 200 μL
ABCG1-BACE2-20-GOGR 20 (40 μL) 200 μL
ABCG1-BACE2-20-GOAQ 20 (40 μL) 200 μL
ABCG1-BACE2-20-GRRE 20 (40 μL) 200 μL
ABCG1-BACE2-20-GROR 20 (40 μL) 200 μL
ABCG1-BACE2-20-GRGO 20 (40 μL) 200 μL
ABCG1-BACE2-20-GRGR 20 (40 μL) 200 μL
ABCG1-BACE2-20-GRAQ 20 (40 μL) 200 μL
ABCG1-BACE2-20-AQRE 20 (40 μL) 200 μL
ABCG1-BACE2-20-AQOR 20 (40 μL) 200 μL
ABCG1-BACE2-20-AQGO 20 (40 μL) 200 μL
ABCG1-BACE2-20-AQGR 20 (40 μL) 200 μL
ABCG1-BACE2-20-AQAQ 20 (40 μL) 200 μL

ABCG1 Gene Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]

Gene Name: ATP Binding Cassette Subfamily G Member 1

Chromosome: CHR21: 43619798 -43717354

Locus: 21q22.3

BACE2 Gene Summary

This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Gene Name: Beta-site APP-cleaving Enzyme 2

Chromosome: CHR21: 42539727 -42648524

Locus: 21q22.2-q22.3

Gene Diseases

The ABCG1 BACE2 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.