ABCG1-BACE2 Fusion FISH Probe
The ABCG1-BACE2 Fusion FISH Probe is used to confirm a fusion of the ABCG1 and BACE2 genes. The fusion of the ABCG1 and BACE2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABCG1-BACE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-RERE | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-REOR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-REGO | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-REGR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-REAQ | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-ORRE | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-OROR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-ORGO | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GORE | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GOOR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GOGO | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GOGR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GRRE | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GROR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GRGO | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GRGR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-AQRE | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-AQOR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-AQGO | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-AQGR | 20 (40 μL) | 200 μL |
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| ABCG1-BACE2-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCG1 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily G Member 1
Chromosome: CHR21: 43619798 -43717354
Locus: 21q22.3
BACE2 Gene Summary
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Beta-site APP-cleaving Enzyme 2
Chromosome: CHR21: 42539727 -42648524
Locus: 21q22.2-q22.3
Gene Diseases
The ABCG1 BACE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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