ABCC4-ABCB4 Fusion FISH Probe
The ABCC4-ABCB4 Fusion FISH Probe is used to confirm a fusion of the ABCC4 and ABCB4 genes. The fusion of the ABCC4 and ABCB4 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABCC4-ABCB4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-RERE | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-REOR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-REGO | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-REGR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-REAQ | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-ORRE | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-OROR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-ORGO | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GORE | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GOOR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GOGO | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GOGR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GRRE | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GROR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GRGO | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GRGR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-AQRE | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-AQOR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-AQGO | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-AQGR | 20 (40 μL) | 200 μL |
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| ABCC4-ABCB4-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCB4 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily B Member 4
Chromosome: CHR7: 87031360 -87105019
Locus: 7q21.12
ABCC4 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Name: ATP Binding Cassette Subfamily C Member 4
Chromosome: CHR13: 95672082 -95953687
Locus: 13q32.1
Gene Diseases
The ABCC4 ABCB4 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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