ABCC3-BCAN Fusion FISH Probe
The ABCC3-BCAN Fusion FISH Probe is used to confirm a fusion of the ABCC3 and BCAN genes. The fusion of the ABCC3 and BCAN genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABCC3-BCAN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-RERE | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-REOR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-REGO | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-REGR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-REAQ | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-ORRE | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-OROR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-ORGO | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GORE | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GOOR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GOGO | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GOGR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GRRE | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GROR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GRGO | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GRGR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-AQRE | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-AQOR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-AQGO | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-AQGR | 20 (40 μL) | 200 μL |
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| ABCC3-BCAN-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCC3 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily C Member 3
Chromosome: CHR17: 48712217 -48769063
Locus: 17q21.33
BCAN Gene Summary
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Name: Brevican
Chromosome: CHR1: 156611739 -156629320
Locus: 1q23.1
Gene Diseases
The ABCC3 BCAN Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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