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ABCC1-PRKCB Fusion FISH Probe

The ABCC1-PRKCB Fusion FISH Probe is used to confirm a fusion of the ABCC1 and PRKCB genes. The fusion of the ABCC1 and PRKCB genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads. Typical turnaround time for this product is 7-14 days after purchase.

ABCC1-PRKCB Fusion FISH Probe

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping

Download FISH ProtocolDownload Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
ABCC1-PRKCB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABCC1-PRKCB-20-RERE 20 (40 μL) 200 μL
ABCC1-PRKCB-20-REOR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-REGO 20 (40 μL) 200 μL
ABCC1-PRKCB-20-REGR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-REAQ 20 (40 μL) 200 μL
ABCC1-PRKCB-20-ORRE 20 (40 μL) 200 μL
ABCC1-PRKCB-20-OROR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-ORGO 20 (40 μL) 200 μL
ABCC1-PRKCB-20-ORAQ 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GORE 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GOOR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GOGO 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GOGR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GOAQ 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GRRE 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GROR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GRGO 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GRGR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-GRAQ 20 (40 μL) 200 μL
ABCC1-PRKCB-20-AQRE 20 (40 μL) 200 μL
ABCC1-PRKCB-20-AQOR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-AQGO 20 (40 μL) 200 μL
ABCC1-PRKCB-20-AQGR 20 (40 μL) 200 μL
ABCC1-PRKCB-20-AQAQ 20 (40 μL) 200 μL

ABCC1 Gene Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]

Gene Name: ATP Binding Cassette Subfamily C Member 1

Chromosome: CHR16: 16043433 -16236930

Locus: 16p13.11

PRKCB Gene Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Gene Name: Protein Kinase C Beta

Chromosome: CHR16: 23847299 -24231932

Locus: 16p12.2-p12.1

Gene Diseases

The ABCC1 PRKCB Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.