ABCB9-EIF2B1 Fusion FISH Probe
The ABCB9-EIF2B1 Fusion FISH Probe is used to confirm a fusion of the ABCB9 and EIF2B1 genes. The fusion of the ABCB9 and EIF2B1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABCB9-EIF2B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-RERE | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-REOR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-REGO | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-REGR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-REAQ | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-ORRE | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-OROR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-ORGO | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GORE | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GOOR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GOGO | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GOGR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GRRE | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GROR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GRGO | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GRGR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-AQRE | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-AQOR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-AQGO | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-AQGR | 20 (40 μL) | 200 μL |
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| ABCB9-EIF2B1-20-AQAQ | 20 (40 μL) | 200 μL |
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EIF2B1 Gene Summary
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Oct 2009]
Gene Name: Eukaryotic Translation Initiation Factor 2B Subunit Alpha
Chromosome: CHR12: 124105569 -124118323
Locus: 12q24.31
ABCB9 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011]
Gene Name: ATP Binding Cassette Subfamily B Member 9
Chromosome: CHR12: 123405497 -123451056
Locus: 12q24.31
Gene Diseases
The ABCB9 EIF2B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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