ABCA2-TRIM14 Fusion FISH Probe

The ABCA2-TRIM14 Fusion FISH Probe is used to confirm a fusion of the ABCA2 and TRIM14 genes. The fusion of the ABCA2 and TRIM14 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABCA2-TRIM14-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABCA2-TRIM14-20-RERE 20 (40 μL) 200 μL
ABCA2-TRIM14-20-REOR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-REGO 20 (40 μL) 200 μL
ABCA2-TRIM14-20-REGR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-REAQ 20 (40 μL) 200 μL
ABCA2-TRIM14-20-ORRE 20 (40 μL) 200 μL
ABCA2-TRIM14-20-OROR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-ORGO 20 (40 μL) 200 μL
ABCA2-TRIM14-20-ORAQ 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GORE 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GOOR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GOGO 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GOGR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GOAQ 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GRRE 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GROR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GRGO 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GRGR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-GRAQ 20 (40 μL) 200 μL
ABCA2-TRIM14-20-AQRE 20 (40 μL) 200 μL
ABCA2-TRIM14-20-AQOR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-AQGO 20 (40 μL) 200 μL
ABCA2-TRIM14-20-AQGR 20 (40 μL) 200 μL
ABCA2-TRIM14-20-AQAQ 20 (40 μL) 200 μL

ABCA2 Gene Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: ATP Binding Cassette Subfamily A Member 2

Chromosome: CHR9: 139901685 -139923374

Locus: 9q34.3

TRIM14 Gene Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

Gene Name: Tripartite Motif Containing 14

Chromosome: CHR9: 100831568 -100881488

Locus: 9q22.33

Gene Diseases

The ABCA2 TRIM14 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.