ABCA12-SGPP2 Fusion FISH Probe
The ABCA12-SGPP2 Fusion FISH Probe is used to confirm a fusion of the ABCA12 and SGPP2 genes. The fusion of the ABCA12 and SGPP2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABCA12-SGPP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-RERE | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-REOR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-REGO | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-REGR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-REAQ | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-ORRE | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-OROR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-ORGO | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GORE | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GOOR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GOGO | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GOGR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GRRE | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GROR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GRGO | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GRGR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-AQRE | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-AQOR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-AQGO | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-AQGR | 20 (40 μL) | 200 μL |
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| ABCA12-SGPP2-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCA12 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily A Member 12
Chromosome: CHR2: 215796265 -216003151
Locus: 2q35
SGPP2 Gene Summary
The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Sphingosine-1-phosphate Phosphatase 2
Chromosome: CHR2: 223289321 -223423617
Locus: 2q36.1
Gene Diseases
The ABCA12 SGPP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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