ABAT-KIAA0430 Fusion FISH Probe

The ABAT-KIAA0430 Fusion FISH Probe is used to confirm a fusion of the ABAT and KIAA0430 genes. The fusion of the ABAT and KIAA0430 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABAT-KIAA0430-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABAT-KIAA0430-20-RERE 20 (40 μL) 200 μL
ABAT-KIAA0430-20-REOR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-REGO 20 (40 μL) 200 μL
ABAT-KIAA0430-20-REGR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-REAQ 20 (40 μL) 200 μL
ABAT-KIAA0430-20-ORRE 20 (40 μL) 200 μL
ABAT-KIAA0430-20-OROR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-ORGO 20 (40 μL) 200 μL
ABAT-KIAA0430-20-ORAQ 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GORE 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GOOR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GOGO 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GOGR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GOAQ 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GRRE 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GROR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GRGO 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GRGR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-GRAQ 20 (40 μL) 200 μL
ABAT-KIAA0430-20-AQRE 20 (40 μL) 200 μL
ABAT-KIAA0430-20-AQOR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-AQGO 20 (40 μL) 200 μL
ABAT-KIAA0430-20-AQGR 20 (40 μL) 200 μL
ABAT-KIAA0430-20-AQAQ 20 (40 μL) 200 μL

ABAT Gene Summary

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: 4-aminobutyrate Aminotransferase

Chromosome: CHR16: 8768443 -8878432

Locus: 16p13.2

Gene Diseases

The ABAT KIAA0430 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.