AATF-GOSR2 Fusion FISH Probe

The AATF-GOSR2 Fusion FISH Probe is used to confirm a fusion of the AATF and GOSR2 genes. The fusion of the AATF and GOSR2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AATF-GOSR2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AATF-GOSR2-20-RERE 20 (40 μL) 200 μL
AATF-GOSR2-20-REOR 20 (40 μL) 200 μL
AATF-GOSR2-20-REGO 20 (40 μL) 200 μL
AATF-GOSR2-20-REGR 20 (40 μL) 200 μL
AATF-GOSR2-20-REAQ 20 (40 μL) 200 μL
AATF-GOSR2-20-ORRE 20 (40 μL) 200 μL
AATF-GOSR2-20-OROR 20 (40 μL) 200 μL
AATF-GOSR2-20-ORGO 20 (40 μL) 200 μL
AATF-GOSR2-20-ORAQ 20 (40 μL) 200 μL
AATF-GOSR2-20-GORE 20 (40 μL) 200 μL
AATF-GOSR2-20-GOOR 20 (40 μL) 200 μL
AATF-GOSR2-20-GOGO 20 (40 μL) 200 μL
AATF-GOSR2-20-GOGR 20 (40 μL) 200 μL
AATF-GOSR2-20-GOAQ 20 (40 μL) 200 μL
AATF-GOSR2-20-GRRE 20 (40 μL) 200 μL
AATF-GOSR2-20-GROR 20 (40 μL) 200 μL
AATF-GOSR2-20-GRGO 20 (40 μL) 200 μL
AATF-GOSR2-20-GRGR 20 (40 μL) 200 μL
AATF-GOSR2-20-GRAQ 20 (40 μL) 200 μL
AATF-GOSR2-20-AQRE 20 (40 μL) 200 μL
AATF-GOSR2-20-AQOR 20 (40 μL) 200 μL
AATF-GOSR2-20-AQGO 20 (40 μL) 200 μL
AATF-GOSR2-20-AQGR 20 (40 μL) 200 μL
AATF-GOSR2-20-AQAQ 20 (40 μL) 200 μL

GOSR2 Gene Summary

This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. [provided by RefSeq, Mar 2016]

Gene Name: Golgi SNAP Receptor Complex Member 2

Chromosome: CHR17: 45000485 -45018733

Locus: 17q21.32

AATF Gene Summary

The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]

Gene Name: Apoptosis Antagonizing Transcription Factor

Chromosome: CHR17: 35306174 -35414171

Locus: 17q12

Gene Diseases

The AATF GOSR2 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.