AATF-AP2B1 Fusion FISH Probe
The AATF-AP2B1 Fusion FISH Probe is used to confirm a fusion of the AATF and AP2B1 genes. The fusion of the AATF and AP2B1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AATF-AP2B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| AATF-AP2B1-20-AQAQ | 20 (40 μL) | 200 μL |
|
AP2B1 Gene Summary
The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Adaptor Related Protein Complex 2 Beta 1 Subunit
Chromosome: CHR17: 33914281 -34053436
Locus: 17q12
AATF Gene Summary
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: Apoptosis Antagonizing Transcription Factor
Chromosome: CHR17: 35306174 -35414171
Locus: 17q12
Gene Diseases
The AATF AP2B1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|