AASS-CADPS2 Fusion FISH Probe
The AASS-CADPS2 Fusion FISH Probe is used to confirm a fusion of the AASS and CADPS2 genes. The fusion of the AASS and CADPS2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AASS-CADPS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-RERE | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-REOR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-REGO | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-REGR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-REAQ | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-ORRE | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-OROR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-ORGO | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GORE | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GOOR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GOGO | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GOGR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GRRE | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GROR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GRGO | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GRGR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-AQRE | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-AQOR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-AQGO | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-AQGR | 20 (40 μL) | 200 μL |
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| AASS-CADPS2-20-AQAQ | 20 (40 μL) | 200 μL |
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AASS Gene Summary
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008]
Gene Name: Aminoadipate-semialdehyde Synthase
Chromosome: CHR7: 121713597 -121784344
Locus: 7q31.32
CADPS2 Gene Summary
This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Gene Name: Calcium Dependent Secretion Activator 2
Chromosome: CHR7: 121958477 -122526813
Locus: 7q31.32
Gene Diseases
The AASS CADPS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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